HTLV1 Target gene Detail Information

> ZNF487 Gene Search Result

Gene Information

Gene Name	ZNF487
Gene ID	642819
Gene Full Name	zinc finger protein 487
Gene Alias	KRBO1; ZNF487P
Transcripts	ENSG00000243660
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	B1APH4
HGNC ID	HGNC:23488
VEGA ID	OTTHUMG00000185507
String ID	9606.ENSP00000392335
PharmGKB ID	PA143485525

Target gene [ZNF487] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6010644	chr10	29	1		30	View
6029171	chr10	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZNF487 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF487 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).