HIV Target gene Detail Information

> ZNF484 Gene Search Result

Gene Information

Gene Name	ZNF484
Gene ID	83744
Gene Full Name	zinc finger protein 484
Gene Alias	BA526D8.4
Transcripts	ENSG00000127081
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nuclear membrane;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q5JVG2
HGNC ID	HGNC:23385
VEGA ID	OTTHUMG00000020236
String ID	9606.ENSP00000378881
PharmGKB ID	PA134992184

Target gene [ZNF484] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015474	chr9		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF484 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF484 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF484 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF484 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).