HBV Target gene Detail Information

> ZNF48 Gene Search Result


Gene Information
Gene Name ZNF48
Gene ID 197407
Gene Full Name zinc finger protein 48
Gene Alias ZNF553
Transcripts ENSG00000180035
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q96MX3
HGNC ID HGNC:13114
VEGA ID OTTHUMG00000048195
String ID 9606.ENSP00000480262
PharmGKB ID PA37689
Target gene [ZNF48] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002990 chr16 174 5 179 View
1002991 chr16 174 5 179 View
1006623 chr16 36 36 View
1404876 chr16 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF48 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF48 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).