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HTLV1 Target gene Detail Information

> ZNF461 Gene Search Result


Gene Information
Gene Name ZNF461
Gene ID 92283
Gene Full Name zinc finger protein 461
Gene Alias GIOT1; HZF28; GIOT-1
Transcripts ENSG00000197808
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;Nucleoli;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8TAF7
HGNC ID HGNC:21629
VEGA ID OTTHUMG00000180832
OMIM ID 608640
String ID 9606.ENSP00000467931
PharmGKB ID PA145149895
Target gene [ZNF461] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001650 chr19 375 1 1 377 View
6012642 chr19 19 3 22 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ZNF461 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF461 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ZNF461 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF461 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).