HIV Target gene Detail Information

> ZNF449 Gene Search Result

Gene Information

Gene Name	ZNF449
Gene ID	203523
Gene Full Name	zinc finger protein 449
Gene Alias	ZSCAN19
Transcripts	ENSG00000173275
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q6P9G9
HGNC ID	HGNC:21039
VEGA ID	OTTHUMG00000022478
OMIM ID	300627
String ID	9606.ENSP00000339585
PharmGKB ID	PA134920699

Target gene [ZNF449] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016063	chrX				0	View
4016698	chrX				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF449 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF449 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).