HBV Target gene Detail Information

> ZNF423 Gene Search Result


Gene Information
Gene Name ZNF423
Gene ID 23090
Gene Full Name zinc finger protein 423
Gene Alias OAZ; Roaz; hOAZ; Ebfaz; JBTS19; NPHP14; ZFP423; Zfp104
Transcripts ENSG00000102935
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q2M1K9
HGNC ID HGNC:16762
VEGA ID OTTHUMG00000173491
OMIM ID 604557
String ID 9606.ENSP00000455426
PharmGKB ID PA134903681
Target gene [ZNF423] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003940 chr16 59 37 4 100 View
1015212 chr16 2 2 View
1402136 chr16 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF423 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF423 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).