HIV Target gene Detail Information

> ZNF395 Gene Search Result


Gene Information
Gene Name ZNF395
Gene ID 55893
Gene Full Name zinc finger protein 395
Gene Alias PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14
Transcripts ENSG00000186918
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9H8N7
HGNC ID HGNC:18737
VEGA ID OTTHUMG00000102137
OMIM ID 609494
String ID 9606.ENSP00000340494
PharmGKB ID PA134978145
Target gene [ZNF395] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008254 chr8 16 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZNF395 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF395 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ZNF395 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF395 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).