HBV Target gene Detail Information

> ZNF385B Gene Search Result


Gene Information
Gene Name ZNF385B
Gene ID 151126
Gene Full Name zinc finger protein 385B
Gene Alias ZNF533
Transcripts ENSG00000144331
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q569K4
HGNC ID HGNC:26332
VEGA ID OTTHUMG00000154559
OMIM ID 612344
String ID 9606.ENSP00000386845
PharmGKB ID PA162410114
Target gene [ZNF385B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002236 chr2 35 152 122 309 View
1003197 chr2 12 99 47 158 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF385B expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF385B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).