HTLV1 Target gene Detail Information

> ZNF33A Gene Search Result

Gene Information

Gene Name	ZNF33A
Gene ID	7581
Gene Full Name	zinc finger protein 33A
Gene Alias	KOX2; KOX5; KOX31; NF11A; ZNF11; ZNF33; ZZAPK; ZNF11A
Transcripts	ENSG00000189180
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Nucleoli fibrillar center;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q06730
HGNC ID	HGNC:13096
VEGA ID	OTTHUMG00000017983
OMIM ID	194521
String ID	9606.ENSP00000304268
PharmGKB ID	PA37671

Target gene [ZNF33A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002974	chr10	193	1		194	View
6007563	chr10	47	2	5	54	View
6014268	chr10	1	4	12	17	View
6014269	chr10	1	4	12	17	View
6019297	chr10	7	1		8	View
6020635	chr10	6			6	View
6021607	chr10	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZNF33A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF33A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZNF33A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF33A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ZNF33A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZNF33A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).