HBV Target gene Detail Information

> ZNF254 Gene Search Result


Gene Information
Gene Name ZNF254
Gene ID 9534
Gene Full Name zinc finger protein 254
Gene Alias BMZF-5; ZNF539; ZNF91L; HD-ZNF1
Transcripts ENSG00000213096
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID O75437
HGNC ID HGNC:13047
VEGA ID OTTHUMG00000183394
OMIM ID 604768
String ID 9606.ENSP00000349494
PharmGKB ID PA37625
Target gene [ZNF254] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015276 chr19 2 2 View
1402222 chr19 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF254 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF254 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).