HIV Target gene Detail Information

> ZNF253 Gene Search Result


Gene Information
Gene Name ZNF253
Gene ID 56242
Gene Full Name zinc finger protein 253
Gene Alias BMZF1; BMZF-1; ZNF411
Transcripts ENSG00000256771
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID O75346
HGNC ID HGNC:13497
VEGA ID OTTHUMG00000182369
OMIM ID 606954
String ID 9606.ENSP00000468720
PharmGKB ID PA37785
Target gene [ZNF253] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007177 chr19 10 10 20 View
4009147 chr19 12 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZNF253 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF253 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).