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HBV Target gene Detail Information

> ZNF248 Gene Search Result


Gene Information
Gene Name ZNF248
Gene ID 57209
Gene Full Name zinc finger protein 248
Gene Alias bA162G10.3
Transcripts ENSG00000198105
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8NDW4
HGNC ID HGNC:13041
VEGA ID OTTHUMG00000017980
String ID 9606.ENSP00000379208
PharmGKB ID PA37619
Target gene [ZNF248] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010126 chr10 13 13 View
1010127 chr10 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ZNF248 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ZNF248 expression: Low -> High
Lollipop of ZNF248 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ZNF248 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF248 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF248 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).