HIV Target gene Detail Information

> ZNF224 Gene Search Result


Gene Information
Gene Name ZNF224
Gene ID 7767
Gene Full Name zinc finger protein 224
Gene Alias BMZF2; KOX22; ZNF27; BMZF-2; ZNF233; ZNF255
Transcripts ENSG00000267680
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear membrane;Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9NZL3
HGNC ID HGNC:13017
VEGA ID OTTHUMG00000182313
OMIM ID 194555
String ID 9606.ENSP00000337368
PharmGKB ID PA37596
Target gene [ZNF224] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005408 chr19 33 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZNF224 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF224 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ZNF224 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF224 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).