HIV Target gene Detail Information

> ZNF18 Gene Search Result

Gene Information

Gene Name	ZNF18
Gene ID	7566
Gene Full Name	zinc finger protein 18
Gene Alias	HDSG1; KOX11; ZNF535; Zfp535; ZKSCAN6; ZSCAN38
Transcripts	ENSG00000154957
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	P17022
HGNC ID	HGNC:12969
VEGA ID	OTTHUMG00000178307
OMIM ID	194524
String ID	9606.ENSP00000315664
PharmGKB ID	PA37551

Target gene [ZNF18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007908	chr17	3	8	6	17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF18 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF18 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF18 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).