HIV Target gene Detail Information

> ZNF174 Gene Search Result

Gene Information

Gene Name	ZNF174
Gene ID	7727
Gene Full Name	zinc finger protein 174
Gene Alias	ZSCAN8
Transcripts	ENSG00000103343
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Actin filaments;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q15697
HGNC ID	HGNC:12963
VEGA ID	OTTHUMG00000129358
OMIM ID	603900
String ID	9606.ENSP00000268655
PharmGKB ID	PA37545

Target gene [ZNF174] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007046	chr16	19	2		21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF174 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF174 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF174 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF174 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).