HIV Target gene Detail Information

> ZNF146 Gene Search Result


Gene Information
Gene Name ZNF146
Gene ID 7705
Gene Full Name zinc finger protein 146
Gene Alias OZF
Transcripts ENSG00000167635
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoli;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q15072
HGNC ID HGNC:12931
VEGA ID OTTHUMG00000180511
OMIM ID 601505
String ID 9606.ENSP00000400391
PharmGKB ID PA37518
Target gene [ZNF146] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4009401 chr19 11 11 View
4009402 chr19 11 11 View
4009403 chr19 11 11 View
4009404 chr19 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZNF146 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF146 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ZNF146 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF146 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).