HIV Target gene Detail Information

> ZNF136 Gene Search Result

Gene Information

Gene Name	ZNF136
Gene ID	7695
Gene Full Name	zinc finger protein 136
Gene Alias	pHZ-20
Transcripts	ENSG00000196646
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	P52737
HGNC ID	HGNC:12920
VEGA ID	OTTHUMG00000156429
OMIM ID	604078
String ID	9606.ENSP00000344162
PharmGKB ID	PA37508

Target gene [ZNF136] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010716	chr19	8			8	View
4014923	chr19		2		2	View
4014924	chr19	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZNF136 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF136 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZNF136 expression and immune infiltrating cell level correlation result in HIV+ samples
ZNF136 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).