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HBV Target gene Detail Information

> ZNF114 Gene Search Result


Gene Information
Gene Name ZNF114
Gene ID 163071
Gene Full Name zinc finger protein 114
Transcripts ENSG00000178150
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8NC26
HGNC ID HGNC:12894
VEGA ID OTTHUMG00000183191
OMIM ID 603996
String ID 9606.ENSP00000469998
PharmGKB ID PA37483
Target gene [ZNF114] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011859 chr19 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ZNF114 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ZNF114 expression: Low -> High
Lollipop of ZNF114 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ZNF114 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZNF114 expression and immune infiltrating cell level correlation result in HBV+ samples
ZNF114 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).