HIV Target gene Detail Information

> ZFX Gene Search Result

Gene Information

Gene Name	ZFX
Gene ID	7543
Gene Full Name	zinc finger protein X-linked
Gene Alias	ZNF926
Transcripts	ENSG00000005889
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	P17010
HGNC ID	HGNC:12869
VEGA ID	OTTHUMG00000021264
OMIM ID	314980
String ID	9606.ENSP00000368475
PharmGKB ID	PA37458

Target gene [ZFX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003153	chrX	4	55	9	68	View
4005082	chrX	31	4	1	36	View
4007482	chrX	15	4		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZFX expression and immune infiltrating cell level correlation result in HIV+ samples
ZFX expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZFX expression and immune infiltrating cell level correlation result in HIV+ samples
ZFX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).