HIV Target gene Detail Information

> ZFPL1 Gene Search Result


Gene Information
Gene Name ZFPL1
Gene ID 7542
Gene Full Name zinc finger protein like 1
Gene Alias MCG4; D11S750
Transcripts ENSG00000162300
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O95159
HGNC ID HGNC:12868
VEGA ID OTTHUMG00000165597
String ID 9606.ENSP00000294258
PharmGKB ID PA37457
Target gene [ZFPL1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001886 chr11 108 17 125 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ZFPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZFPL1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ZFPL1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZFPL1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).