HBV Target gene Detail Information

> ZFHX4 Gene Search Result

Gene Information

Gene Name	ZFHX4
Gene ID	79776
Gene Full Name	zinc finger homeobox 4
Gene Alias	ZFH4; ZHF4
Transcripts	ENSG00000091656
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q86UP3
HGNC ID	HGNC:30939
VEGA ID	OTTHUMG00000164557
OMIM ID	606940
String ID	9606.ENSP00000430497
PharmGKB ID	PA134986366

Target gene [ZFHX4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009542	chr8	7	7	1	15	View
1011972	chr8	8			8	View
1011974	chr8	8			8	View
1015818	chr8		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ZFHX4 expression and immune infiltrating cell level correlation result in HBV+ samples
ZFHX4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).