HIV Target gene Detail Information

> ZFC3H1 Gene Search Result

Gene Information

Gene Name	ZFC3H1
Gene ID	196441
Gene Full Name	zinc finger C3H1-type containing
Gene Alias	CSRC2; PSRC2; CCDC131
Transcripts	ENSG00000133858
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Intermediate filaments;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O60293
HGNC ID	HGNC:28328
VEGA ID	OTTHUMG00000169545
String ID	9606.ENSP00000368017
PharmGKB ID	PA164727644

Target gene [ZFC3H1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003819	chr12	14	30	10	54	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZFC3H1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZFC3H1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZFC3H1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZFC3H1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).