HIV Target gene Detail Information

> ZEB2 Gene Search Result

Gene Information

Gene Name	ZEB2
Gene ID	9839
Gene Full Name	zinc finger E-box binding homeobox 2
Gene Alias	SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1
Transcripts	ENSG00000169554
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	O60315
HGNC ID	HGNC:14881
VEGA ID	OTTHUMG00000187624
OMIM ID	605802
String ID	9606.ENSP00000454157
PharmGKB ID	PA162409612

Target gene [ZEB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000690	chr2	7	294	15	316	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZEB2 expression and immune infiltrating cell level correlation result in HIV+ samples
ZEB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZEB2 expression and immune infiltrating cell level correlation result in HIV+ samples
ZEB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).