HBV Target gene Detail Information

> ZEB1 Gene Search Result

Gene Information

Gene Name	ZEB1
Gene ID	6935
Gene Full Name	zinc finger E-box binding homeobox 1
Gene Alias	BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1
Transcripts	ENSG00000148516
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	P37275
HGNC ID	HGNC:11642
VEGA ID	OTTHUMG00000017907
OMIM ID	189909
String ID	9606.ENSP00000354487
PharmGKB ID	PA162409589

Target gene [ZEB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011690	chr10	8			8	View
1011691	chr10	8			8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ZEB1 expression and immune infiltrating cell level correlation result in HBV+ samples
ZEB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).