HIV Target gene Detail Information

> ZC3HAV1 Gene Search Result

Gene Information

Gene Name	ZC3HAV1
Gene ID	56829
Gene Full Name	zinc finger CCCH-type containing, antiviral 1
Gene Alias	ZAP; ZC3H2; ARTD13; PARP13; FLB6421; ZC3HDC2
Transcripts	ENSG00000105939
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q7Z2W4
HGNC ID	HGNC:23721
VEGA ID	OTTHUMG00000157471
OMIM ID	607312
String ID	9606.ENSP00000242351
PharmGKB ID	PA134944289

Target gene [ZC3HAV1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004414	chr7	13	3	28	44	View
4007216	chr7	16	4		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZC3HAV1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZC3HAV1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZC3HAV1 expression and immune infiltrating cell level correlation result in HIV+ samples
ZC3HAV1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).