HIV Target gene Detail Information

> ZC3H4 Gene Search Result

Gene Information

Gene Name	ZC3H4
Gene ID	23211
Gene Full Name	zinc finger CCCH-type containing 4
Gene Alias	C19orf7
Transcripts	ENSG00000130749
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9UPT8
HGNC ID	HGNC:17808
VEGA ID	OTTHUMG00000183442
String ID	9606.ENSP00000253048
PharmGKB ID	PA162409534

Target gene [ZC3H4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000948	chr19	6	192	43	241	View
4001670	chr19	14	70	58	142	View
4001793	chr19	13	61	58	132	View
4002013	chr19	20	40	58	118	View
4002194	chr19	12	37	58	107	View
4002617	chr19	52	34	1	87	View
4006191	chr19	25	1		26	View
4007618	chr19	15	3		18	View
4009245	chr19	7	5		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZC3H4 expression and immune infiltrating cell level correlation result in HIV+ samples
ZC3H4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZC3H4 expression and immune infiltrating cell level correlation result in HIV+ samples
ZC3H4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).