HTLV1 Target gene Detail Information

> ZC3H12B Gene Search Result

Gene Information

Gene Name	ZC3H12B
Gene ID	340554
Gene Full Name	zinc finger CCCH-type containing 12B
Gene Alias	MCPIP2; CXorf32
Transcripts	ENSG00000102053
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Golgi apparatus;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5HYM0
HGNC ID	HGNC:17407
VEGA ID	OTTHUMG00000021719
OMIM ID	300889
String ID	9606.ENSP00000340839
PharmGKB ID	PA134942463

Target gene [ZC3H12B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000291	chrX	1887	164	272	2323	View
6017517	chrX	7		3	10	View
6021165	chrX	6			6	View
6021520	chrX	4	2		6	View
6023963	chrX	4			4	View
6025524	chrX	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZC3H12B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZC3H12B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZC3H12B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZC3H12B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ZC3H12B expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZC3H12B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).