HTLV1 Target gene Detail Information

> ZBTB7A Gene Search Result

Gene Information

Gene Name	ZBTB7A
Gene ID	51341
Gene Full Name	zinc finger and BTB domain containing 7A
Gene Alias	LRF; FBI1; FBI-1; TIP21; ZBTB7; ZNF857A; pokemon
Transcripts	ENSG00000178951
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	O95365
HGNC ID	HGNC:18078
VEGA ID	OTTHUMG00000181792
OMIM ID	605878
String ID	9606.ENSP00000323670
PharmGKB ID	PA134885165

Target gene [ZBTB7A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001457	chr19	337	34	59	430	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ZBTB7A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZBTB7A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ZBTB7A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZBTB7A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ZBTB7A expression and immune infiltrating cell level correlation result in HTLV1+ samples
ZBTB7A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).