HIV Target gene Detail Information

> ZBTB25 Gene Search Result

Gene Information

Gene Name	ZBTB25
Gene ID	7597
Gene Full Name	zinc finger and BTB domain containing 25
Gene Alias	KUP; ZNF46; C14orf51
Transcripts	ENSG00000089775
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	P24278
HGNC ID	HGNC:13112
VEGA ID	OTTHUMG00000141310
OMIM ID	194541
String ID	9606.ENSP00000476746
PharmGKB ID	PA37687

Target gene [ZBTB25] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002373	chr14	93	4		97	View
4005240	chr14	28	6		34	View
4013431	chr14	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ZBTB25 expression and immune infiltrating cell level correlation result in HIV+ samples
ZBTB25 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ZBTB25 expression and immune infiltrating cell level correlation result in HIV+ samples
ZBTB25 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).