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HBV Target gene Detail Information

> ZBTB10 Gene Search Result


Gene Information
Gene Name ZBTB10
Gene ID 65986
Gene Full Name zinc finger and BTB domain containing 10
Gene Alias RINZF
Transcripts ENSG00000205189
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96DT7
HGNC ID HGNC:30953
VEGA ID OTTHUMG00000155016
OMIM ID 618576
String ID 9606.ENSP00000387462
PharmGKB ID PA134883318
Target gene [ZBTB10] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001627 chr8 14 514 44 572 View
1015700 chr8 2 2 View
1015701 chr8 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ZBTB10 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ZBTB10 expression: Low -> High
Lollipop of ZBTB10 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ZBTB10 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ZBTB10 expression and immune infiltrating cell level correlation result in HBV+ samples
ZBTB10 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).