HIV Target gene Detail Information

> YBX1 Gene Search Result

Gene Information

Gene Name	YBX1
Gene ID	4904
Gene Full Name	Y-box binding protein 1
Gene Alias	YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
Transcripts	ENSG00000065978
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P67809
HGNC ID	HGNC:8014
VEGA ID	OTTHUMG00000007523
OMIM ID	154030
String ID	9606.ENSP00000361626
PharmGKB ID	PA31791

Target gene [YBX1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006319	chr1	25			25	View
4009489	chr1	11			11	View
4015769	chr1		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of YBX1 expression and immune infiltrating cell level correlation result in HIV+ samples
YBX1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of YBX1 expression and immune infiltrating cell level correlation result in HIV+ samples
YBX1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).