HBV Target gene Detail Information

> XYLT1 Gene Search Result


Gene Information
Gene Name XYLT1
Gene ID 64131
Gene Full Name xylosyltransferase 1
Gene Alias XT1; XTI; XT-I; DBQD2; XYLTI; PXYLT1; xylT-I
Transcripts ENSG00000285395
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Endoplasmic reticulum;Predicted to be secreted;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins
Uniport_ID Q86Y38
HGNC ID HGNC:15516
VEGA ID OTTHUMG00000129975
OMIM ID 608124
String ID 9606.ENSP00000261381
PharmGKB ID PA37973
Target gene [XYLT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004458 chr16 40 7 33 80 View
1005262 chr16 40 6 11 57 View
1006363 chr16 38 1 39 View
1010587 chr16 11 11 View
1011850 chr16 7 1 8 View
1012519 chr16 5 1 6 View
1012591 chr16 5 1 6 View
1013696 chr16 3 1 4 View
1400513 chr3 0 View
1403673 chr16 40 7 33 80 View
1403674 chr16 40 6 11 57 View
1403751 chr16 5 1 6 View
1403932 chr16 3 1 4 View
1403933 chr16 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of XYLT1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
XYLT1 expression: Low -> High
Lollipop of XYLT1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of XYLT1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of XYLT1 expression and immune infiltrating cell level correlation result in HBV+ samples
XYLT1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).