HBV Target gene Detail Information

> XRCC4 Gene Search Result

Gene Information

Gene Name	XRCC4
Gene ID	7518
Gene Full Name	X-ray repair cross complementing 4
Gene Alias	SSMED
Transcripts	ENSG00000152422
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID	Q13426
HGNC ID	HGNC:12831
VEGA ID	OTTHUMG00000131319
OMIM ID	194363
String ID	9606.ENSP00000421491
Drugbank ID	BE0001585
PharmGKB ID	PA37423

Target gene [XRCC4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006100	chr5	20	11	12	43	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of XRCC4 expression and immune infiltrating cell level correlation result in HBV+ samples
XRCC4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).