HIV Target gene Detail Information

> XPOT Gene Search Result

Gene Information

Gene Name	XPOT
Gene ID	11260
Gene Full Name	exportin for tRNA
Gene Alias	XPO3
Transcripts	ENSG00000184575
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transporters
Uniport_ID	O43592
HGNC ID	HGNC:12826
VEGA ID	OTTHUMG00000168794
OMIM ID	603180
String ID	9606.ENSP00000327821
PharmGKB ID	PA37419

Target gene [XPOT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003797	chr12	17	37		54	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of XPOT expression and immune infiltrating cell level correlation result in HIV+ samples
XPOT expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of XPOT expression and immune infiltrating cell level correlation result in HIV+ samples
XPOT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).