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HBV Target gene Detail Information

> XPO6 Gene Search Result


Gene Information
Gene Name XPO6
Gene ID 23214
Gene Full Name exportin 6
Gene Alias EXP6; RANBP20
Transcripts ENSG00000169180
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96QU8
HGNC ID HGNC:19733
VEGA ID OTTHUMG00000176782
OMIM ID 608411
String ID 9606.ENSP00000302790
PharmGKB ID PA134989996
Target gene [XPO6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002155 chr16 280 18 28 326 View
1402781 chr16 280 18 28 326 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of XPO6 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
XPO6 expression: Low -> High
Lollipop of XPO6 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of XPO6 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of XPO6 expression and immune infiltrating cell level correlation result in HBV+ samples
XPO6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).