HIV Target gene Detail Information

> XPO4 Gene Search Result

Gene Information

Gene Name	XPO4
Gene ID	64328
Gene Full Name	exportin 4
Gene Alias	exp4
Transcripts	ENSG00000132953
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID	Q9C0E2
HGNC ID	HGNC:17796
VEGA ID	OTTHUMG00000016528
OMIM ID	611449
String ID	9606.ENSP00000255305
PharmGKB ID	PA134866468

Target gene [XPO4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003034	chr13	27	27	18	72	View
4003133	chr13	31	25	13	69	View
4007248	chr13	10	10		20	View
4012150	chr13		5		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of XPO4 expression and immune infiltrating cell level correlation result in HIV+ samples
XPO4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of XPO4 expression and immune infiltrating cell level correlation result in HIV+ samples
XPO4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).