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HTLV1 Target gene Detail Information

> XK Gene Search Result


Gene Information
Gene Name XK
Gene ID 7504
Gene Full Name X-linked Kx blood group
Gene Alias KX; NA; NAC; X1k; XKR1
Transcripts ENSG00000047597
Virus HTLV1
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoplasm;Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Blood group antigen proteins, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID P51811
HGNC ID HGNC:12811
VEGA ID OTTHUMG00000033171
OMIM ID 314850
String ID 9606.ENSP00000367879
PharmGKB ID PA37410
Target gene [XK] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000238 chr3 2308 183 174 2665 View
6001399 chr3 35 135 281 451 View
6004157 chr4 22 91 14 127 View
6027249 chrX 2 2 View
6030556 chr4 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of XK expression and immune infiltrating cell level correlation result in HTLV1+ samples
XK expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of XK expression and immune infiltrating cell level correlation result in HTLV1+ samples
XK expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of XK expression and immune infiltrating cell level correlation result in HTLV1+ samples
XK expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).