HBV Target gene Detail Information

> XIAP Gene Search Result

Gene Information

Gene Name	XIAP
Gene ID	331
Gene Full Name	X-linked inhibitor of apoptosis
Gene Alias	API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
Transcripts	ENSG00000101966
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P98170
HGNC ID	HGNC:592
VEGA ID	OTTHUMG00000022336
OMIM ID	300079
String ID	9606.ENSP00000360242
Drugbank ID	BE0001156
PharmGKB ID	PA25361
FDA Approved Drug	Emapalumab-lzsg

Target gene [XIAP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011997	chrX	8			8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of XIAP expression and immune infiltrating cell level correlation result in HBV+ samples
XIAP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).