HIV Target gene Detail Information

> XCR1 Gene Search Result

Gene Information

Gene Name	XCR1
Gene ID	2829
Gene Full Name	X-C motif chemokine receptor 1
Gene Alias	GPR5; CCXCR1
Transcripts	ENSG00000173578
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P46094
HGNC ID	HGNC:1625
VEGA ID	OTTHUMG00000133449
OMIM ID	600552
String ID	9606.ENSP00000310405
PharmGKB ID	PA35037

Target gene [XCR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008087	chr3	14	2		16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of XCR1 expression and immune infiltrating cell level correlation result in HIV+ samples
XCR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).