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HPV Target gene Detail Information

> XAGE3 Gene Search Result


Gene Information
Gene Name XAGE3
Gene ID 170626
Gene Full Name X antigen family member 3
Gene Alias PLAC6; GAGED4; XAGE-3; pp9012; CT12.3a; CT12.3b
Transcripts ENSG00000171402
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8WTP9
HGNC ID HGNC:14618
VEGA ID OTTHUMG00000021587
OMIM ID 300740
String ID 9606.ENSP00000303061
PharmGKB ID PA33376
Target gene [XAGE3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403814 chrX 0 View
5404784 chrX 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of XAGE3 expression and immune infiltrating cell level correlation result in HPV+ samples
XAGE3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).