HIV Target gene Detail Information

> WTAP Gene Search Result

Gene Information

Gene Name	WTAP
Gene ID	9589
Gene Full Name	WT1 associated protein
Gene Alias	Mum2
Transcripts	ENSG00000146457
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15007
HGNC ID	HGNC:16846
VEGA ID	OTTHUMG00000015933
OMIM ID	605442
String ID	9606.ENSP00000351141
PharmGKB ID	PA134864847

Target gene [WTAP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005180	chr6	32	3		35	View
4010381	chr6	7	1	1	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of WTAP expression and immune infiltrating cell level correlation result in HIV+ samples
WTAP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of WTAP expression and immune infiltrating cell level correlation result in HIV+ samples
WTAP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).