HPV Target gene Detail Information

> WNT5A Gene Search Result


Gene Information
Gene Name WNT5A
Gene ID 7474
Gene Full Name Wnt family member 5A
Gene Alias hWNT5A
Transcripts ENSG00000114251
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted secreted proteins
Gene Function Suppressor gene & Oncogene
Uniport_ID P41221
HGNC ID HGNC:12784
VEGA ID OTTHUMG00000158361
OMIM ID 164975
String ID 9606.ENSP00000264634
PharmGKB ID PA37385
Target gene [WNT5A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5300198 chr3 15 15 139 169 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of WNT5A expression and immune infiltrating cell level correlation result in HPV+ samples
WNT5A expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of WNT5A expression and immune infiltrating cell level correlation result in HPV+ samples
WNT5A expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of WNT5A expression and immune infiltrating cell level correlation result in HPV+ samples
WNT5A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).