HTLV1 Target gene Detail Information

> WNT3A Gene Search Result


Gene Information
Gene Name WNT3A
Gene ID 89780
Gene Full Name Wnt family member 3A
Transcripts ENSG00000154342
Virus HTLV1
Gene Type protein coding
HPA Location Info Vesicles;Predicted to be secreted;
HPA Protein Class Info Predicted secreted proteins
Uniport_ID P56704
HGNC ID HGNC:15983
VEGA ID OTTHUMG00000037593
OMIM ID 606359
String ID 9606.ENSP00000284523
PharmGKB ID PA38074
Target gene [WNT3A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6020288 chr1 6 1 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of WNT3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
WNT3A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of WNT3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
WNT3A expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of WNT3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
WNT3A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).