HIV Target gene Detail Information

> WIPF1 Gene Search Result


Gene Information
Gene Name WIPF1
Gene ID 7456
Gene Full Name WAS/WASL interacting protein family member 1
Gene Alias WIP; WAS2; PRPL-2; WASPIP
Transcripts ENSG00000115935
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID O43516
HGNC ID HGNC:12736
VEGA ID OTTHUMG00000132334
OMIM ID 602357
String ID 9606.ENSP00000376330
PharmGKB ID PA162409189
Target gene [WIPF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001007 chr2 147 47 33 227 View
4001932 chr2 63 3 56 122 View
4002116 chr2 39 38 34 111 View
4004161 chr2 36 5 7 48 View
4006693 chr2 15 7 1 23 View
4008958 chr2 13 13 View
4100008 chr2 14 8 13 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of WIPF1 expression and immune infiltrating cell level correlation result in HIV+ samples
WIPF1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of WIPF1 expression and immune infiltrating cell level correlation result in HIV+ samples
WIPF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).