HTLV1 Target gene Detail Information

> WDR88 Gene Search Result

Gene Information

Gene Name	WDR88
Gene ID	126248
Gene Full Name	WD repeat domain 88
Gene Alias	PQWD
Transcripts	ENSG00000166359
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6ZMY6
HGNC ID	HGNC:26999
VEGA ID	OTTHUMG00000180342
String ID	9606.ENSP00000348129
PharmGKB ID	PA162409139

Target gene [WDR88] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007676	chr19	44	9		53	View
6010007	chr19	8	25		33	View
6010011	chr19	8	25		33	View
6022997	chr19	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of WDR88 expression and immune infiltrating cell level correlation result in HTLV1+ samples
WDR88 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of WDR88 expression and immune infiltrating cell level correlation result in HTLV1+ samples
WDR88 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).