HIV Target gene Detail Information

> WDR6 Gene Search Result

Gene Information

Gene Name	WDR6
Gene ID	11180
Gene Full Name	WD repeat domain 6
Transcripts	ENSG00000178252
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NNW5
HGNC ID	HGNC:12758
VEGA ID	OTTHUMG00000133546
OMIM ID	606031
String ID	9606.ENSP00000378857
PharmGKB ID	PA37362

Target gene [WDR6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001081	chr3	218			218	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of WDR6 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of WDR6 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).