HIV Target gene Detail Information

> WDR45B Gene Search Result

Gene Information

Gene Name	WDR45B
Gene ID	56270
Gene Full Name	WD repeat domain 45B
Gene Alias	WIPI3; WDR45L; WIPI-3; NEDSBAS
Transcripts	ENSG00000141580
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5MNZ6
HGNC ID	HGNC:25072
VEGA ID	OTTHUMG00000150146
OMIM ID	609226
String ID	9606.ENSP00000376139
PharmGKB ID	PA134894387

Target gene [WDR45B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012086	chr17	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of WDR45B expression and immune infiltrating cell level correlation result in HIV+ samples
WDR45B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).