HIV Target gene Detail Information

> WDR26 Gene Search Result

Gene Information

Gene Name	WDR26
Gene ID	80232
Gene Full Name	WD repeat domain 26
Gene Alias	CDW2; GID7; MIP2; SKDEAS
Transcripts	ENSG00000162923
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Mitochondria;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H7D7
HGNC ID	HGNC:21208
VEGA ID	OTTHUMG00000037636
OMIM ID	617424
String ID	9606.ENSP00000408108
PharmGKB ID	PA134907873

Target gene [WDR26] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003732	chr1	54	1		55	View
4005029	chr1	13	23		36	View
4005030	chr1	13	23		36	View
4005031	chr1	13	23		36	View
4005032	chr1	13	23		36	View
4006944	chr1	18	4		22	View
4008578	chr1	11	3		14	View
4008865	chr1	7	6		13	View
4008911	chr1	3	10		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of WDR26 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR26 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of WDR26 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR26 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).