HIV Target gene Detail Information

> WDR20 Gene Search Result

Gene Information

Gene Name	WDR20
Gene ID	91833
Gene Full Name	WD repeat domain 20
Gene Alias	DMR
Transcripts	ENSG00000140153
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8TBZ3
HGNC ID	HGNC:19667
VEGA ID	OTTHUMG00000171753
OMIM ID	617741
String ID	9606.ENSP00000406084
PharmGKB ID	PA134936678

Target gene [WDR20] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002782	chr14	6	52	22	80	View
4007603	chr14	1	17		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of WDR20 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR20 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of WDR20 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR20 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).