HIV Target gene Detail Information

> WDR20 Gene Search Result


Gene Information
Gene Name WDR20
Gene ID 91833
Gene Full Name WD repeat domain 20
Gene Alias DMR
Transcripts ENSG00000140153
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8TBZ3
HGNC ID HGNC:19667
VEGA ID OTTHUMG00000171753
OMIM ID 617741
String ID 9606.ENSP00000406084
PharmGKB ID PA134936678
Target gene [WDR20] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002782 chr14 6 52 22 80 View
4007603 chr14 1 17 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of WDR20 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR20 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of WDR20 expression and immune infiltrating cell level correlation result in HIV+ samples
WDR20 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).