HBV Target gene Detail Information

> WDR17 Gene Search Result


Gene Information
Gene Name WDR17
Gene ID 116966
Gene Full Name WD repeat domain 17
Transcripts ENSG00000150627
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8IZU2
HGNC ID HGNC:16661
VEGA ID OTTHUMG00000160791
OMIM ID 609005
String ID 9606.ENSP00000280190
PharmGKB ID PA38181
Target gene [WDR17] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002671 chr4 223 2 225 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of WDR17 expression and immune infiltrating cell level correlation result in HBV+ samples
WDR17 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).